{"id":1208,"date":"2022-02-14T22:37:47","date_gmt":"2022-02-14T22:37:47","guid":{"rendered":"https:\/\/cbdcliniccare.com\/cbn-may-alleviate-alzheimers\/"},"modified":"2022-02-14T23:07:41","modified_gmt":"2022-02-14T23:07:41","slug":"cbn-may-alleviate-alzheimers","status":"publish","type":"post","link":"https:\/\/cbdcliniccare.com\/it\/cbn-may-alleviate-alzheimers\/","title":{"rendered":"La CBN pu\u00f2 alleviare la malattia di Alzheimers"},"content":{"rendered":"[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” shape_type=””][vc_column column_padding=”padding-3-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left-right” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” column_border_width=”none” column_border_style=”solid” bg_image_animation=”none” offset=”vc_hidden-sm vc_hidden-xs”][vc_custom_heading text=”La CBN pu\u00f2 alleviare la malattia di Alzheimers”][divider line_type=”No Line” custom_height=”15″][vc_column_text]Una ricerca innovativa ha scoperto che il cannabinolo (CBN), uno dei composti meno famosi della cannabis, pu\u00f2 potenzialmente aiutare a prevenire e trattare malattie neurodegenerative legate all’et\u00e0, come l’Alzheimer.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Gli scienziati hanno una comprensione completa delle propriet\u00e0 e degli effetti del THC e del CBD, due composti della cannabis che sono diventati ben noti negli ultimi anni e analizzati nella ricerca per decenni. Tuttavia, meno si sa sulle propriet\u00e0 terapeutiche del cannabinolo.
\nOra, un team di ricercatori di Salk ha condotto uno studio rivoluzionario, scoprendo che la CBN protegge le cellule nervose dai danni ossidativi, un importante motore della morte cellulare. I risultati possono aiutare a concepire nuove strategie che utilizzano il cannabinolo per mitigare una serie di malattie neurodegenerative.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Pamela Maher, l’autrice senior della ricerca e docente di ricerca e responsabile del Laboratorio di Neurobiologia Cellulare di Salk, ha affermato: “Abbiamo scoperto che il cannabinolo protegge i neuroni dallo stress ossidativo e dalla morte cellulare, due dei principali contributori all’Alzheimer. Questa scoperta potrebbe un giorno portare allo sviluppo di nuove terapie per trattare questa malattia e altri disturbi neurodegenerativi, come il morbo di Parkinson.”[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Lo studio \u00e8 stato finanziato dal National Institutes of Health, dal Paul F. Glenn Center for Biology of Aging Research presso il Salk Institute, un Innovation Award dal Salk Institute, dalla Shiley Foundation, dalla Bundy Foundation e dall’Universit\u00e0 della California di San Diego.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” shape_type=””][vc_column column_padding=”padding-3-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left-right” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” column_border_width=”none” column_border_style=”solid” bg_image_animation=”none” offset=”vc_hidden-sm vc_hidden-xs”][image_with_animation image_url=”1203″ animation=”Fade In” hover_animation=”none” alignment=”center” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default”][divider line_type=”No Line” custom_height=”15″][vc_custom_heading text=”Cos’\u00e8 il cannabinolo?”][vc_column_text]Il cannabinolo \u00e8 derivato dalla pianta della cannabis, e sebbene sia molecolarmente simile al THC, non condivide le stesse propriet\u00e0 psicoattive e successivamente \u00e8 meno pesantemente regolato dalla FDA. Una precedente ricerca eseguita dal team di Maher ha identificato che il cannabinolo ha qualit\u00e0 neuroprotettive, con questa nuova ricerca che illumina il meccanismo della CBN che protegge le cellule cerebrali da danni e morte.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Scoprire le propriet\u00e0 neuroprotettive[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Il team ha studiato il processo di ossitosi – altrimenti noto come ferroptosi – che si ritiene si verifichi in un cervello in et\u00e0 avanzata e pu\u00f2 causare la malattia di Alzheimer. L’ossitosi pu\u00f2 essere innescata a causa della graduale perdita dell’antiossidante glutatione, con conseguente danno alle cellule neurali e morte attraverso l’ossidazione lipidica. I ricercatori hanno somministrato cannabinolo alle cellule nervose nel loro studio e poi hanno introdotto un agente per stimolare il danno ossidativo.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]I risultati hanno dimostrato che la CBN funziona proteggendo i mitocondri che alimentano le cellule all’interno dei neuroni; l’ossidazione induce i mitocondri a raggomitolarsi come ciambelle nelle cellule danneggiate, un cambiamento che si manifesta nelle cellule anziane delle persone affette dal morbo di Alzheimer. Il trattamento CBN ha impedito che ci\u00f2 accadesse ai mitocondri e ha permesso loro di continuare a funzionare correttamente. Per rafforzare i loro risultati, il team ha replicato l’esperimento nelle cellule nervose senza mitocondri; qui, CBN non ha pi\u00f9 mostrato il suo effetto protettivo.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]”Siamo stati in grado di dimostrare direttamente che il mantenimento della funzione mitocondriale era specificamente richiesto per gli effetti protettivi del composto”, ha detto Maher.
\nInoltre, il team ha identificato che il cannabinolo non ha attivato i recettori della cannabis, il che fa s\u00ec che i cannabinoidi producano una risposta psicoattiva, il che significa che potrebbe essere somministrato senza che un individuo diventi “alto”.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Zhibin Liang, il primo autore della ricerca e ricercatore post-dottorato nel laboratorio di Maher, ha commentato: “La CBN non \u00e8 una sostanza controllata come il THC, il composto psicotropo della cannabis, e le prove hanno dimostrato che la CBN \u00e8 sicura negli animali e negli esseri umani. E poich\u00e9 la CBN funziona indipendentemente dai recettori dei cannabinoidi, la CBN potrebbe anche funzionare in un’ampia variet\u00e0 di cellule con un ampio potenziale terapeutico.”[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]”La disfunzione mitocondriale \u00e8 implicata nei cambiamenti nei vari tessuti, non solo nel cervello e nell’invecchiamento, quindi il fatto che questo composto sia in grado di mantenere la funzione mitocondriale suggerisce che potrebbe avere pi\u00f9 benefici al di l\u00e0 del contesto della malattia di Alzheimer”, ha detto Maher.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][divider line_type=”No Line” custom_height=”15″][vc_column_text]Vieni a CBD CLINIC CARE per Pharma Grade CBN per tutte le tue esigenze di formulazione …[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][\/vc_column][\/vc_row][vc_row type=”full_width_content” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” shape_type=””][vc_column column_padding=”padding-6-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left-right” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” tablet_text_alignment=”default” phone_text_alignment=”default” column_border_width=”none” column_border_style=”solid” bg_image_animation=”none” offset=”vc_hidden-lg vc_hidden-md”][divider line_type=”No Line” custom_height=”15″][vc_custom_heading text=”CBD neuroprotective properties: concentration and memory” google_fonts=”font_family:Abril%20Fatface%3Aregular”][divider line_type=”No Line” custom_height=”15″][vc_column_text]CBD – cannabidiol, a bioactive part of the Cannabis plant is becoming popular due to its potential benefits for the mind and body.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]It would seem that CBD is useful for concentration and memory due to its neuroprotective properties. Some studies confirm a very interesting fact, that CBD plays an important role in mitigating the memory impairment induced by THC.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Implicitly, then, it is suggested that cannabidiol may have concrete properties to support the ability to retain memories.Concentration and Memory Lack of concentration can have troublesome impacts on humans, including loss of time and poor execution of one’s work.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Individuals affected by this condition, may run into endless fatigue that can only exacerbate the situation. As well as concentration, memory plays a vital role in everyday life. Whether in the work field or not, it represents an advantage that can come in handy in times of need.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]It usually lasts about 60 seconds. Long-term memory is the ability to store and remember information for longer periods of time, indefinitely. Long-term memory can be further broken down into different categories, including explicit memory, implicit memory, and autobiographical memory.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n
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Unfortunately, there are several diseases that take over this capacity. Preventing us from being able to relive our fondest memories, or even worse not being able to be autonomous. There is a small but growing amount of scientific evidence showing that CBD can help the brain and improve memory.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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CBD has been found to promote neurogenesis and as a result reduce damage to cognitive function caused by age, disease, and trauma.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][image_with_animation image_url=”1068″ animation=”Fade In” hover_animation=”none” alignment=”” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default”][divider line_type=”No Line” custom_height=”15″][vc_custom_heading text=”How does CBD work?”][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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CBD interacts directly with dopamine in the brain, which is a chemical neurotransmitter responsible for memory, concentration and mental awareness. At the point when an individual possesses lower attention and concentration, this implies that dopamine levels are low.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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Ingesting CBD does not allow for an irregular increase in dopamine levels in the brain. Instead, the correct composition of CBD oil from the right variety will help improve concentration and overall performance at school and at work.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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Keeping the brain healthy as we age is crucial. In an aging brain, age-related cognitive decline is due to many factors ranging from genetics to lifestyle habits, it is also partly due to a decrease in neuroplasticity and neurogenesis.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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Neuroplasticity is the brain’s ability to change and reorganize and is the process through which the processes of all memory and learning occur.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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CBD also acts on trauma, i.e. unpleasant memories. Clinical studies carried out on people who have suffered post-traumatic stress, show how important is the mitigating and relaxing action of CBD in the removal of unpleasant memories.<\/p>\n<\/div>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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Neurogenesis is the birth of new brain cells. Cbd with its neuroprotective properties assists the natural aging process, minimizing damage.<\/p>\n<\/div>\n<\/div>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]\n

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The first effects are stress reduction and a lowering of anxiety and fear.<\/p>\n<\/div>\n<\/div>\n<\/div>\n[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][image_with_animation image_url=”1066″ animation=”Fade In” hover_animation=”none” alignment=”” border_radius=”none” box_shadow=”none” image_loading=”default” max_width=”100%” max_width_mobile=”default”][divider line_type=”No Line” custom_height=”15″][vc_custom_heading text=”Neuroprotective properties”][divider line_type=”No Line” custom_height=”15″][vc_column_text]There is a study, published in 2010 in The British Journal of Psychiatry, in which the effects of CBD and THC on acute memory were compared.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]This study revealed that THC (tetrahydrocannabinol) and CBD (cannabidiol), have different effects on a person’s brain.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]In the brain, THC and CBD act on some of the same receptors – CB1 and CB2 – these receptors affect appetite, pain, memory, and mood.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]Scientists believe that CBD’s neuroprotective effect is due to its action on CB2 receptors. It acts on this particular receptor to generate anti-inflammatory responses in brain cells, therefore, minimizing the damage that could be caused by inflammation.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]A study published in Frontiers in Pharmacology, for example, shows how CBD promotes neurogenesis (neuronal growth and regrowth): basically it reduces and prevents the deterioration of cognitive function.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]The analysis deals with the properties and possible developments of CBD as a neuroprotector in relation to brain damage.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]We can state that CBD, often demonized because it is associated with cannabis, should not be seen as a drug that impairs memory.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]On the contrary, being composed of many active ingredients and cannabinoids, it turns out to be a carrier of favorable effects on our body.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]The analysis deals with the properties and possible developments of CBD as a neuroprotector in relation to brain damage.[\/vc_column_text][divider line_type=”No Line” custom_height=”15″][vc_column_text]They will also be able to assist in the reduction over time, of cognitive disorders related to some neurodegenerative diseases.[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” equal_height=”yes” content_placement=”middle” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” shape_type=””][vc_column column_padding=”padding-3-percent” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”left-right” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_shadow=”none” column_border_radius=”none” column_link_target=”_self” gradient_direction=”left_to_right” overlay_strength=”0.3″…<\/p>\n","protected":false},"author":3,"featured_media":1202,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":{"0":"post-1208","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-research-it"},"yoast_head":"\nLa CBN pu\u00f2 alleviare la malattia di Alzheimers - 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