{"id":1301,"date":"2022-09-25T17:39:11","date_gmt":"2022-09-25T17:39:11","guid":{"rendered":"https:\/\/cbdcliniccare.com\/what-is-cbg\/"},"modified":"2022-09-25T17:58:41","modified_gmt":"2022-09-25T17:58:41","slug":"what-is-cbg","status":"publish","type":"post","link":"https:\/\/cbdcliniccare.com\/it\/what-is-cbg\/","title":{"rendered":"Che Cos&#8217;\u00c8 Cannabigerol (CBG)?"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; equal_height=&#8221;yes&#8221; content_placement=&#8221;middle&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221; shape_type=&#8221;&#8221;][vc_column column_padding=&#8221;padding-3-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;left-right&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221; offset=&#8221;vc_hidden-sm vc_hidden-xs&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;CBG&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]\n<div class=\"elementToProof\">\n<div>Il cannabigerolo (CBG) \u00e8 un tipo di cannabinoide ottenuto dalla pianta di cannabis. Si chiama spesso madre di tutti i cannabinoidi. Questo perch\u00e9 altri cannabinoidi sono derivati dall&#8217;acido cannabigerolico (CBGA), una forma acida di CBG.\u00a0Altri cannabinoidi pi\u00f9 comuni ottenuti da piante di cannabis includono cannabidiolo (CBD) e tetraidrocannabinolo (THC).\u00a0La CBG si trova in quantit\u00e0 inferiori a quelle di altri cannabinoidi nelle piante di cannabis. Nella maggior parte dei ceppi dell&#8217;impianto, solo l&#8217;1% dei CBG si trova rispetto al 20-25% dei CBD o tra il 25 e il 30% del THC.1\u00a0In questo modo i prodotti di consumo derivati dalla cannabinoide sono rari e spesso costosi. Tuttavia, CBG sta crescendo in termini di popolarit\u00e0 a causa dei numerosi vantaggi potenziali offerti dalla cannabinoide.<\/div>\n<\/div>\n[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;Modalit\u00e0 Di Creazione Di CBG&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]La CBG deriva da giovani piante di cannabis, che contengono quantit\u00e0 di CBG superiori a quelle di piante completamente sviluppate.\u00a0Alcuni ceppi di cannabis, come White CBG, Super Glue CBG e Jack Frost CBG, hanno anche un tenore di CBG maggiore rispetto ad altri ceppi. Questi ceppi sono coltivati specificamente per produrre maggiori quantit\u00e0 di CBG.\u00a0Sia il CBD che il THC iniziano come CBGA, una forma acida di CBG. Per questo motivo le piante di cannabis pi\u00f9 giovani contengono concentrazioni superiori di CBG.\u00a0Negli impianti completamente sviluppati con concentrazioni elevate di THC e CBD, si riscontreranno concentrazioni molto basse di CBG. Ci\u00f2 si verifica perch\u00e9 la maggior parte dei CBG \u00e8 gi\u00e0 stata convertita in CBD e THC man mano che l\u2019impianto si \u00e8 sviluppato.\u00a0A causa della difficolt\u00e0 di ottenere CBG, i coltivatori di cannabis hanno sperimentato con l&#8217;incrocio e la manipolazione genetica per aiutare le piante di cannabis a produrre pi\u00f9 CBG.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;Funzionamento di CBG&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]CBG \u00e8 trattata dal sistema endocannabinoide dell\u2019organismo. Il sistema endocannabinoide \u00e8 costituito da molecole e recettori nei nostri corpi che sono responsabili di mantenere i nostri corpi in uno stato ottimale, indipendentemente da quello che accade nel nostro ambiente esterno.\u00a0Nei nostri corpi, il CBG imita endocannabinoidi, i composti naturali che il nostro corpo produce.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][image_with_animation image_url=&#8221;1295&#8243; animation=&#8221;Fade In&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;Recipienti di cannabinoidi del corpo&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]Il nostro corpo contiene due tipi di recettori cannabinoidi: CB1 e CB2. I recettori CB1 si trovano nel sistema nervoso e nel cervello, mentre i recettori CB2 si trovano nel sistema immunitario e in altre aree del corpo.\u00a0La CBG lavora con entrambi i recettori dove si ritiene che rafforzi la funzione di anandamide, un neurotrasmettitore che contribuisce a migliorare il piacere e la motivazione, a regolare l&#8217;appetito e il sonno, e ad alleviare il dolore. A differenza del THC, CBG non ha effetti psicotropi, quindi non \u00e8 un effetto elevato.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;Potenziali benefici di CBG&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]Come la CBD, la CBG \u00e8 stata usata per combattere il dolore senza l&#8217;effetto inebriante dei cannabinoidi come la THC.\u00a0La ricerca dimostra che anche CBG pu\u00f2 avere effetti terapeutici. Tuttavia, gli studi sull&#8217;uomo sono sparsi e sono necessarie ulteriori ricerche.\u00a0Alcuni promettenti studi sugli animali mostrano che CBG potrebbe aiutare a curare alcune condizioni mediche.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][\/vc_column][\/vc_row][vc_row type=&#8221;full_width_content&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; equal_height=&#8221;yes&#8221; content_placement=&#8221;middle&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221; shape_type=&#8221;&#8221;][vc_column column_padding=&#8221;padding-6-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;left-right&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; bg_image_animation=&#8221;none&#8221; offset=&#8221;vc_hidden-lg vc_hidden-md&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]Lately we&#8217;ve been hearing more and more about cannabinoids, especially THC and CBD. But you&#8217;ve probably never heard of cannabichromene, also known as CBC. Discovered over 50 years ago, CBC is considered one of the six outstanding cannabinoids in medical research. It doesn&#8217;t get the same attention as other cannabinoids, but the benefits of the cannabinoid CBC are extremely promising.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]CBC has the same origins as THC and CBD, all of which are derived from cannabigerolic acid (CBGA). Cannabis plants produce CBGA, the precursor to three main cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromene carboxylic acid (CBCA).[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]For CBC, it converts from CBGA to cannabichromene carboxylic acid (CBCA), and then finally to CBC after exposure to heat or ultraviolet light.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][image_with_animation image_url=&#8221;1095&#8243; animation=&#8221;Fade In&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_custom_heading text=&#8221;What is CBC?&#8221;][vc_column_text]Cannabichromene belongs to the family of organic compounds known as cannabinoids. Contained in hemp and different varieties of marijuana, CBC is synthesized after CBCA is exposed to heat and light. However, it is different from most cannabinoids because it has a low affinity for our CB receptors. Instead, CBC binds to TRPV receptors involved in the perceptions of temperature changes and other stimuli at the cellular level. Although CBC can bring benefits individually, most studies have examined the effects of CBC along with other cannabinoids such as CBD and THC. Cannabichromene shows excellent synergy with other cannabinoids, but despite being an important compound within the biological structure of Cannabis sativa, it is only produced in small amounts.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]CBC does not cause intoxication, it does not produce euphoria, like THC. The reason it is not intoxicating is that it binds poorly to CB1 cannabinoid receptors in the brain. But CBC does bind to other receptors in the body, such as vanilloid receptor 1 (TRPV1) and transient potential ankyrin receptor 1 (TRPA1), both of which are linked to pain perception. When CBC activates these receptors, elevated levels of the body&#8217;s natural endocannabinoids, such as anandamide, are released.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p>CBC has separate benefits, but researchers also believe it works in synergy with other cannabinoids, a term known as the entourage effect. This effect of THC working together with CBD is well known, but it is not known whether other cannabinoids also have an entourage effect.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]\n<div id=\"enc-abstract\" class=\"abstract-content selected\">\n<p>Cannabichromene has been shown to block the pain and inflammation associated with osteoarthritis. Cannabinoids such as CBC act on inflammation differently than nonsteroidal anti-inflammatory drugs (NSAIDs) and do not have the side effects of these drugs. In another example of an entourage effect, CBC in combination with THC had a significant anti-inflammatory response in an animal study: together, the two cannabinoids produced a much greater effect on inflammation than separately.<\/p>\n<\/div>\n[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][image_with_animation image_url=&#8221;1097&#8243; animation=&#8221;Fade In&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_custom_heading text=&#8221;CBC Research&#8221;][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]The benefits that CBC would have have far-reaching implications. Below are some medical conditions that can be alleviated by cannabichromene.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]<strong>Cancer<\/strong>[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]Cannabichromene may be a powerful cancer fighter, and the reason might be its interaction with the body\u2019s natural endocannabinoid, anandamide. CBC also appears to inhibit the uptake of anandamide, allowing it to remain longer in the bloodstream.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]A recent study in which tumor growth was initiated in mice (two-stage mouse skin carcinogenesis model)\u00a0<a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jphp.12082\/abstract\">showed cannabinoids<\/a>\u00a0might be effective in inhibiting both inflammation and tumor growth. Since anandamide has been shown to\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25147760\">fight breast cancer<\/a>\u00a0in vitro and in vivo, this shows promise that CBC and other cannabinoids might one day be a chemopreventive agent.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]CBC as a potential cancer fighter was first published in a\u00a0<a href=\"http:\/\/jpet.aspetjournals.org\/content\/318\/3\/1375.long\">2006 study<\/a>\u00a0that looked at cannabinoids other than THC and their possible effects on cancer. While THC is known for its anti-tumor properties for several different forms of cancer, its powerful psychotropic qualities can make it difficult for chemotherapy use. So far, research has found CBC to be the second-most-potent cannabinoid at inhibiting the growth of new cancer cells (CBG\u00a0was the most potent).[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]<strong>Pain and Inflammation<\/strong>[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]Cannabichromene has been shown to\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20942863\">block pain<\/a>\u00a0and inflammation associated with collagen-induced osteoarthritis. Cannabinoids like CBC act on\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22300105\">inflammation differently<\/a>\u00a0than non-steroidal anti-inflammatory drugs (NSAIDs) do, and don\u2019t have the side effects of these medications. In another example of the entourage effect, CBC in combination with THC had significant anti-inflammatory response in a\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2967639\/\">recent animal study<\/a>; together, the two cannabinoids produced a much greater effect on inflammation than by themselves.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]<strong>Brain Cells<\/strong>[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]In a 2013 mouse study, CBC had a\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=The+effect+of+cannabichromene+on+adult+neural+stem%2Fprogenitor+cells\">positive effect<\/a>\u00a0on neural stem progenitor cells (NSPCs), a cell essential to healthy brain function. NSPCs became more viable when in the presence of CBC, and that shows promise because NSPCs differentiate into astroglial cells, the most important cells for maintaining brain homeostasis. The astroglial cells perform a whole\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3181926\/\">host of functions<\/a>, including neurotransmitter direction and defending against oxidative stress. Astroglia counteract many of these issues\u2014oxidative stress, inflammation, toxicity\u2014that create neurological diseases and brain pathologies like Alzheimer\u2019s disease.[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]<strong>Acne<\/strong>[\/vc_column_text][divider line_type=&#8221;No Line&#8221; custom_height=&#8221;15&#8243;][vc_column_text]A research team that had previously shown CBD\u2019s effect on acne studied other cannabinoids,\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27094344\">including CBC<\/a>, for the same effects. Indeed, CBC was shown to be a powerful inhibitor of acne. As a skin disease, acne is characterized by excess sebum production and sebaceous gland inflammation. It turns out that CBC exhibited powerful anti-inflammatory properties and also suppressed excessive lipid production in the sebaceous glands. CBC also reduced levels of arachidonic acid (AA), which is needed to create the lipogenesis. More research is needed, but CBC might just one day become a very powerful antiacne treatment.[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"<p>[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; equal_height=&#8221;yes&#8221; content_placement=&#8221;middle&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221; shape_type=&#8221;&#8221;][vc_column column_padding=&#8221;padding-3-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;left-right&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243;&#8230;<\/p>\n","protected":false},"author":3,"featured_media":1306,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[8],"tags":[],"class_list":{"0":"post-1301","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-research-it"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Che Cos&#039;\u00c8 Cannabigerol (CBG)? 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